How can Duphaston help to conceive a child with infertility and how to take it?
Infertility in women is a very common problem. In order for conception to occur, and the fetus to develop normally, certain favorable conditions are required. One of them is the hormonal background of a woman, in particular, a sufficient level of progesterone.
The development of such a hormone occurs in the female body after ovulation and prepares the body for pregnancy. If it is absent or is synthesized in too small a quantity, then even after fertilization of the egg, a miscarriage will occur, since the fertilized egg will not be able to consolidate in the uterus. To prevent such a situation, doctors often prescribe "Duphaston." This is a hormonal drug that helps the normal carrying of a child with problems with progesterone in the future mother.
What is this drug?
"Duphaston" is available in pill form. They have a white shell and a convex round shape. There is also a risk that the drug can be divided into halves. The drug is sold in boxes of 20-112 tablets (in blisters of 14-20 pieces).
The main ingredient is didrogesterone. In one pill, it is contained in a dosage of 10 mg. The composition is also supplemented with lactose monohydrate, corn starch, hypromellose and other substances, due to which the drug has a dense core and a strong shell.
To buy "Duphaston" in a pharmacy requires a prescription from a doctor. The average price of 20 tablets is 500 rubles. Store at home medication is recommended in a dry place at a temperature of 30 degrees Celsius.
Before use, be sure to check the expiration date on the packaging of tablets, which is 5 years.
How does it affect the female body?
Didrogesterone in the composition of the pills is similar to natural progesterone in its structure and chemical properties, therefore, it acts in the same way as the hormone produced by the corpus luteum. At the same time, the drug has no side effects that are inherent in synthetic progestogens.
Once in the body of a woman, Duphaston selectively affects only the endometrium, causing changes in it that will ensure the normal implantation of the ovum. It replaces progesterone, which in the body of the future mother is not enough or not at all, with the result that the pregnancy remains. The drug does not adversely affect ovulation and the duration of the menstrual cycle.
The absorption of dydrogesterone from the pill occurs in the intestine rather quickly. 2 hours after taking the medicine, its active substance is found in the blood of the woman in the maximum concentration. It binds to proteins and undergoes metabolic changes in the liver. Most of the drug leaves the body with urine in the first day, and the complete elimination of the drug occurs within 72 hours.
Efficiency
"Duphaston" contributes to conception if the cause of infertility of a woman is luteal insufficiency. In such patients, the drug eliminates the deficiency of progesterone, which prevents the child from carrying out normally. The drug also helps with the threat of miscarriage due to a decrease in the level of progesterone in the pregnant woman's body.
However, "Duphaston" can not be called a universal remedy for infertility, because the reasons for which pregnancy does not occur, quite a lot. The problem may not be in the changed hormonal background, but in something else.Then the pills will not help conceive the baby and save the fetus.
That is why you should not take "Duphaston" independently and on the advice of girlfriends. To ensure the need for such hormonal treatment, consultation of a physician is required.
Other indications for the use of pills are irregular menstrual cycle, endometriosis, secondary amenorrhea, dysfunctional uterine bleeding and premenstrual syndrome. With all these problems, Duphaston is designed to replace the missing progesterone.
Instructions for use
The most common single dose for women who want to get pregnant is one tablet. It should be swallowed and washed down with clean water. The "Duphaston" intake for infertility provides for the start of treatment after ovulation. Usually they start taking medicine from the 14th day of the menstrual cycle and drink until 25 days or longer. A more accurate recommendation is given by the attending physician, since the cycle duration is different for different women.
If a woman is planning a pregnancy, taking Duphaston before ovulation should not, so as not to cause changes in the uterine lining too early. To determine the start of the reception for a particular woman, special tests for ovulation are often used, as well as basal temperature graphs and ultrasound scans.
It is recommended to drink the drug at the same interval. If during infertility a woman took a pill at 8 am, then the next day she should drink the medicine around the same time. The duration of such treatment, as a rule, is 6 consecutive menstrual cycles.
Finishing the course "Duphaston", you need to do a pregnancy test with high sensitivity. If taking the drug helped to get pregnant, in any case, the medication is not canceled. He must maintain the body of the future mother for the entire first trimester, and sometimes even longer (until the 16th to 20th obstetric week). If a woman took "Duphaston" for 6 menstrual cycles, but the pregnancy never occurred, additional examination is required.
Since the drug is hormonal, for the safe cancellation of such an agent, a gradual decrease in the dose is required. Sharply throw "Duphaston" can not. If a patient takes a whole pill, then before discontinuing the medication, she must first take the medicine half a tablet, then 1/4 pill. Only then can treatment be stopped.
Treatment regimens for other indications are different. With the threat of miscarriage, the patient immediately give 40 mg - four tablets. Then the woman takes one tablet every 8 hours (several days) until the risk of abortion is eliminated.
If a woman has endometriosis, which can also act as one of infertility-causing factors, Duphaston can be administered two or three times, from 5 to 25 days of the cycle. Sometimes with this disease, the doctor prescribes a continuous reception for several months, which leads to a regression of lesions, elimination of discomfort symptoms and the onset of a long-awaited pregnancy.
What should be considered when using?
There are contraindications, among which one should particularly highlight the hypersensitivity to pills and serious liver disease. If the expectant mother has any diseases, there have been problems with childbearing earlier or the woman is breastfeeding the baby, the attending physician should answer the question about the use of “Duphaston”.
Sometimes pills cause unwanted side effects, such as an allergic rash or headache. In some patients, Duphaston can cause anemia, edema, bleeding from the uterus, and other dangerous symptoms.When they occur, a medical examination and additional examination are required, after which the expectant mother is prescribed another treatment.
Do not exceed the dosage of the medicine prescribed by the doctor. There were no cases when an excessive dose of “Duphaston” caused poisoning, but in case of an accidental overdose, it is recommended to consult a doctor (especially if there are any negative symptoms).
With other drugs "Duphaston" is compatible, but the simultaneous use of any other means (for example, drugs "Metformin" and "Siofor" with pre-diabetes or polycystic ovaries) is better to discuss with your doctor. This also applies to folk recipes that help to get pregnant - for example, the use of sage.
Reviews
Women who are planning a pregnancy and treat infertility, in most cases, respond to "Duphaston" positively. This hormonal agent is praised for its effective action and good tolerance. Reviews of doctors also confirm the effectiveness of the drug, so it is often prescribed to preserve pregnancy.
Weaknesses, mood changes, weight gain and other negative effects during the reception of "Duphaston" are usually not observed. Of the minuses most often noted the high price of tablets, but many women believe that it is fully justified by the excellent efficacy of the drug.
Analogs
If the use of "Duphaston" is not possible, the doctor may advise taking "Utrozhestan" instead. This drug also helps eliminate the deficiency of progesterone, support conception and prevent the occurrence of problems in the early stages. The main differences of "Utrozhestan" are the composition (its active component is represented by micronized progesterone) and the dosage form (the product is produced in capsules).
In addition, the use of "Utrozhestan" is possible not only inside, but also in another way. Capsules are inserted into the vagina, which is important for strong toxicosis at the beginning of pregnancy. However, the drug can provoke the occurrence of side effects: in the form of drowsiness, bad mood, lethargy and other symptoms.
On the use of the drug "Duphaston" when planning pregnancy, see the following video.
